Tunable Nanoscale Metal-Organic Frameworks for Cancer Therapy

Nanomedicine - nMOFs

The nanomedicine division of the Lin lab has grown rapidly in recent years and become a major component of the group’s work. We have developed tunable nanoscale MOFs that can be loaded with small molecules to probe intracellular conditions and for anticancer efficacy. nMOFs can be excited by light from the visible spectrum to X-rays for radiotherapy and to potentiate checkpoint blockade immunotherapy.

Nanoscale Coordination Polymers for Drug Delivery and Targeted Cancer Therapy

Nanomedicine - NCPs

Cancer is a major public health problem around the world that still faces significant obstacles in clinical treament settings. Nanoscale coordination polymers are self-assembled materials capable of carrying various therapeutics. We are particularly focused on stabilizing highly reactive compounds with significant anticancer properties which has not been harnassed to its full potential.

Metal-Organic Frameworks for Highly Efficient Single-Site Heterogeneous Catalysis

Sustainable Catalysis

Benefit from the unique molecular structure and site-isolation effect, MOFs could serve as a great platform for designing single-site solid catalysts with unique selectivity and exceptional activity, demonstrating potential application in sustainable catalysis and asymmetric catalysis. MOF catalysts were shown to be highly active for a wide range of reactions, including broad-scope hydrogenations, CH functionalizations, and (hetero)arene dearomatizations.

Metal-Organic Frameworks and Metal-Organic Layers for Renewable Energy Applications

Renewable Energy

Sunlight is a highly underutilized energy source with potential to solve the world's energy problems. We surmise that MOFs can integrate different molecular components into a functional water splitting system for this purpose.

Recent News and Group Photos

The Lin Group

Recent News

June 11, 2020

Congratulations Xuanyu

Congratulations to Xuanyu Feng for winning the University of Chicago Chemistry Department's 2020 Seymour Goodman Research Fellowship!

June 11, 2020

Congratulations Guangxu

Congratulations to Guangxu Lan for winning the University of Chicago Chemistry Department's 2020 Elizabeth R. Norton Prize for Excellence in Research in Chemistry!

The Lin Group

Group Photos